New evidence confirms COVID-19 vaccines are overwhelmingly safe::More than 38 million COVID-19 vaccine doses have been administered in Ontario as of Oct. 8, with 23,002 reports of adverse reactions, an incidence of 0.06 per cent, Public Health Ontario says

    • Altima NEO@lemmy.zip
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      8 months ago

      I guess whatever it takes to convince the skeptics. Though I figure nothing will convince them once they’ve made up their mind.

      • kescusay@lemmy.world
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        8 months ago

        I don’t like calling them “skeptics,” because what they really are is super-gullible with regards to conspiracy theories.

          • CleoTheWizard@lemmy.world
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            8 months ago

            Step 1. Ask what someone thinks about vaccinations Step 2. Ask them what they think about evolution Step 3. Ask about climate change Step 4. Ask about what church they go to

            You will learn so much of this overlaps. So much.

            • LillyPip@lemmy.world
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              8 months ago

              Flat earth. Crystals. Cupping.

              Anything to avoid the reality that we’re fucking up society and the planet in favour of ‘we can fix it with woo’ or ‘it’s preordained that we’re all gonna die in god’s wrath-fire’. Neither will lift a finger to fix things.

              Nobody wants to live in reality because it’s scary.

        • PsychedSy@sh.itjust.works
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          8 months ago

          There was real reason to be skeptical at first. mRNA vaccines have been in the works for decades and they had just gotten some that work well, then rushed it through. Drug companies aren’t known for being conservative with claims when there’s money to be made.

        • Rozz@lemmy.sdf.org
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          8 months ago

          “I don’t know… those first fifty studies of vaccine safety didn’t sway me. Maybe 51 will”

      • Player2@sopuli.xyz
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        8 months ago

        Cannot use logic to convince someone whose argument isn’t logical in the first place

        • darkdemize@sh.itjust.works
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          8 months ago

          I’ve always preferred it phrased as “You can’t reason someone out of a position they didn’t reason themselves into,” but same energy.

          • Hobo@lemmy.world
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            8 months ago

            I always preferred the Mark Twain quote, “Never argue with an idiot. They will drag you down to their level and beat you with experience.” Because I’ve been beaten bloody with that experience on more than one occasion.

  • Flying Squid@lemmy.world
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    8 months ago

    Okay, if you say so, because I died six months after getting the first one like they said I would. Now I’m a magnetic 5G zombie.

  • NocturnalMorning@lemmy.world
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    8 months ago

    Amazing what all the efficacy and safety studies said before is still true. It was true before, but now it’s also true.

    • SuckMyWang@lemmy.world
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      They’re not safe. They’re 0.06% harmful. That number is probably a lie too, in reality with all the cover ups and bad incentives the number could be as high as 0.1% harmful, that means 40% of cases were covered up or hidden by nurses and doctors who actively went against their hippocratic oath and did something malicious and counter effective to their job. And they don’t even clearly define what harmful is. How many of those 0.1% had mild head aches or nausea? Everyone is stupid but me.

      /s

      But in all seriousness I’m not sure if it’s better to admit that it’s not 100% safe because a lot of people think they will be the unlucky one out of 1000 to get a headache or a mild rash or the 1 out of 100000 that has something more severe. People who are generally anti vax have a hard time grasping these numbers and also seem to be completely wilfully blind to the increased danger from getting actual Covid. They think they’ll be fine and either won’t get it or it won’t be bad yet at the same time think they’ll be the unlucky one to get sick from the vaccine

      • NocturnalMorning@lemmy.world
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        I usually tell people that it’s safer than birth control. 1 in 1000 women experience severe complications from birth control, and we hand that stuff out like candy.

        • ciapatri@sh.itjust.works
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          8 months ago

          So true. Sadly it’s often those same types of people against vaccines who are against birth control as well.

          • NocturnalMorning@lemmy.world
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            8 months ago

            Depends on if people are willing to listen to facts of incidence of actual adverse effects from the vaccine or not, something like 1 in 2.6 million people will see adverse side effects (depending on source of statistic). Also depends on what health issue you’re looking for issues with. But the overwhelming concensus is that the vaccine is safe. 1 in 1000 is orders of magnitude larger than the covid vaccine adverse effects.

  • kandoh@reddthat.com
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    8 months ago

    There was a 50/50 split in the US Senate when the vaccine came out. Every member of that group was vaccinated. They were the first members of the population to be vaccinated. If any of the ancient senators had died, the balance of power would have shifted in a huge way.

    • darth_tiktaalik@lemmy.ml
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      8 months ago

      Sometimes the goalposts are moved and merged with goalposts from other conspiracy theories.

      When 5g wasn’t the end of humanity it became the trigger for a zombie virus…hidden in the vaccine!

      Wonder what third thing will become the new first domino to knock over the 5g and vaccine dominoes.

      • fubo@lemmy.world
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        8 months ago

        Conspiracism is not truth-tracking. It’s rooted in an emotional response to feelings of lack of control. By saying false things and getting away with it, the conspiracist feels greater control over their life. “You can’t stop me from lying, therefore I have power.”

        Hence why authoritarians love conspiracism: authoritarianism promises that if you repeat the doctrine and smash the Leader’s designated enemies (the “conspiracy”), you will regain the control that was taken from you. This also illustrates why “left” authoritarianism (e.g. Stalinism, Maoism) is really rightist: it does not actually offer freedom or equality, but rather rigid hierarchy and escalating falsehood and cruelty.

        If you follow Nazism, Stalin, Hamas, Trump, or Netanyahu and smash the designated enemies who the Leader tells you have been conspiring against your nation … you do not get freedom, you just eventually become the next enemy to be smashed. Of course really your Leader has built up the enemy to threaten you: authoritarians never seek peace, because peace removes the need to fear and hate.

        (None of this is new. Orwell and Sartre both described it in the 1940s.)

        • SCB@lemmy.world
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          8 months ago

          This kind of inappropriately equates conspiracy theories and conservatism but I assure you that the anti-GMO, 9/11 Truther, and even the original vaccine pushback were not from the right

          There’s even crossover. The New Age/NESARA movement has a pipeline directly into Qanon, a movement at opposite views to NA stuff.

      • WolfhoundRO@lemmy.world
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        It’s almost like those people are happily waiting for this type of panopticonic apocalyptic event to happen just to be proven right the only time in their entire miserable lives

    • db2@sopuli.xyz
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      8 months ago

      Can’t get voted out if nobody’s left to vote. taps forehead

  • k110111@feddit.de
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    8 months ago

    Guys the reason this study is important is because covid vaccines used revolutionary technology, they were the first to use mRNA based protein. If you remember we sequenced its genome within 40 days the making the vaccine was considerably easy. This is the main reason it took only 2 years for the vaccine to be made compared to years of development for other vaccines.

    • Match!!@pawb.social
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      8 months ago

      It also means that, with this new vaccine technology, we can develop vaccines faster and faster

        • nickwitha_k (he/him)@lemmy.sdf.org
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          8 months ago

          Pretty sure that mRNA printers are indeed a thing. But, you’ll probably have better efficiency if you only use it for the template and use RNA-copying enzymes for the bulk of the work.

            • nickwitha_k (he/him)@lemmy.sdf.org
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              8 months ago

              I studied this stuff back in uni, is really fascinating, though, I’m more familiar with DNA amplification via Polymerase Chain Reaction (PCR).

              If you’re interested, I’ll give some details here and a link to a neat video. Effectively, there is an enzyme in our cells called DNA Polymerase. It literally scans a strand of DNA and copies it. In PCR, they use a solution of nucleotides (building blocks of DNA) and the DNA Polymerase extracted from a heat-loving microbe. The DNA to be copied (amplified) is added, and then the temperature maintained at the enzyme’s optimal temperature (higher than usual for other organisms). The solution is allowed to “stew” for a set amount of time, then, filtered to separate the DNA (lots of copies of the original) from everything else.

              A similar process can be done using an RNA polymerase (possibly modified) in order to amplify mRNA. So, once the template is printed, it gets put in the solution and RNA polymerases go brrrrrr.

              https://youtu.be/wJyUtbn0O5Y?si=Gkz8B87iY-35GvuZ

  • JdW@lemmy.world
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    8 months ago

    We always knew/suspected this. But the ones that do the fearmongering around vaccines will not be interested in facts…

    • r3df0x ✡️✝☪️@7.62x54r.ru
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      8 months ago

      Not just that, but a lot of them see it as resistance to authority, even if they don’t think there’s a serious risk. This is inevitably what happens when things get forced and mandates get imposed. It naturally causes people to push back against it.

      • BreakDecks@lemmy.ml
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        No, this is what happens in a rigidly individualistic western countries like the USA, UK, and Australia where people act like children screaming “you can’t tell me what to do!”, even when it’s just the health department asking you to stay safe.

        There were no forced vaccine mandates in the USA, so I don’t really know what you’re talking about when you say that this was inevitable. Right-wingers just pretended that there was a mandate so that they could do performative resistance, but you might have noticed, there was no government-imposed punishment for refusing, just the natural consequence of drowning in your own sputum in the ICU.

        • r3df0x ✡️✝☪️@7.62x54r.ru
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          8 months ago

          Various employers imposed mandates, so there were mandates.

          When neo-fascists try to impose things, that naturally creates resentment. All the people calling for mandates are the reason the reason why there was resistance.

          • jmanes@lemmy.world
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            8 months ago

            Do you also think laws requiring you to wear a seatbelt is “neo-fascist?”

              • emergencyfood@sh.itjust.works
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                8 months ago

                Vaccines work when everyone uses them. There are a small number of people who cannot be vaccinated due to medical reasons. They rely on others being vaccinated. So when a lot of people who can take the vaccine refuse to do so, they put these people in danger.

          • EatATaco@lemm.ee
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            8 months ago

            You’ve got yourself very turned around: the only reason there were talk of mandates is because we knew that, without them, people wouldn’t get the vaccine. Fear of vaccines long predates any mandates. It basically started the minute the first vaccine was developed.

            I’m not saying no one refused it because of talk of mandates, but the overall trend would be that without a strong incentive, some people would not get it, whether it just because of laziness, procrastination, or simply being on the fence about it.

      • EatATaco@lemm.ee
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        8 months ago

        Yeah, so much of it is just contrarianism. These people think that if they blindly reject everything that comes from an official source that they are substantially different than the people who blindly accept everything that comes from an official source.

        • r3df0x ✡️✝☪️@7.62x54r.ru
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          Experts have lied repeatedly and trust in them is at an all time low. If it wasn’t for the talk of mandates, more people would have got the vaccine. Pushback is a natural consequence of trying to force things.

          • EatATaco@lemm.ee
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            8 months ago

            Experts have lied repeatedly

            A completely vague statement - which is almost certainly untrue or a gross misrepresentation of reality - that basically justifies believing whatever you want. I’ve seen this plenty throughout my life, but it’s become especially popular since the start of the pandemic.

  • Cringe2793@lemmy.world
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    What’s the point of this? The people who already believe the vaccine is safe already know it. Those that don’t believe it’s safe aren’t gonna read this OR the report. They’ll claim it’s some sort of propaganda.

    • Jackiedoodle@lemmy.world
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      It’s important simply to do just for the benefit of science going forward. We need to look at the long term effects of medicines. Usually we do that prior to release. It also protects you from the propoganda. Someone may throw out crazy statistics at you but you’ll have this study in your back pocket so you can be like “yeah it’s crazy” and dismiss don’t debate.

      And try not to get too downtrodden with humanity. Not everyone is a too far gone. Some are just a little lost.

      • TWeaK@lemm.ee
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        8 months ago

        Exactly this. What’s annoying is how people twist the process along the way.

        For example, with the AstraZeneca vaccine there was this overblown controversy over blood clots. Every time you stick someone with a needle, their blood will clot, and there’s a chance that a chunk of this clot will break off into the blood stream. Sometimes, the thing you’re injecting makes it more likely to happen, and as such we closely monitor new injections to determine whether or not the issue is significant. AstraZeneca (or any other covid vaccine) has been shown to not significantly increase the risk of blood clots over any other injection - but that didn’t stop politicians (eg Boris Johnson in the UK) to parrot on about the handful of people who did develop blood clots as if it were a real issue. Of course, this led to AstraZeneca no longer being offered as a vaccine for many people; instead, Pfizer and Moderna vaccines were used. Wouldn’t you know it, Boris is personally invested in these companies. He shooed away the non-profit vaccine in favour of the for profit pharmaceutical mega-corporations that pay him dividends. And, of course, his statements actually reduced the uptake of vaccines in general.

      • paddirn@lemmy.world
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        8 months ago

        Yeah, given how quickly alot of these were rushed out, due to the emergency we were in, there really should be follow-up research to prove their safety and efficacy. If only to provide additional evidence to anti-vaxxers who will argue against it. Even if the threat of Covid is seemingly behind us, who’s to say we’re not right back here in the next 5/10/20 years with the next pandemic that comes?

        • Hamartiogonic@sopuli.xyz
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          8 months ago

          Some people have proposed that covid could become an endemic, meaning that there are always pockets of covid brewing somewhere. Annual flu vaccines could be accompanied with annual covid vaccines. If that really happens, we need to know more about the safety of the vaccine. Instead of being an exceptional emergency, it’s just “business as usual”, so proper studies are needed.

          Convincing anti-vaxxers is impossible, because that conversation doesn’t follow the rules of a debate. Instead, the resulting monologue is a symptom of mental instability, and there isn’t much you can do about it.

    • gastationsushi@lemmy.world
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      8 months ago

      Misinformation works though. Antivaxer are rentlenless and they are always releasing studies to prove their lies. Combine that with social media algorithms that love controversy and this shit gets deadly.

      To put it in perspective, the USA could easily have more people die of covid this year than fentanyl ODs but everyone is acting like the battle is over.

    • dangblingus@lemmy.dbzer0.com
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      8 months ago

      It’s about noise. There needs to be more noise made that the vaccines are safe to protect future generations from falling down the same misinformation rabbit holes.

    • GreenM@lemmy.world
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      8 months ago

      There are people who will state internet article’s titles as facts. so it’s good to fight misinformation by information.

    • RickyRigatoni@lemmy.ml
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      8 months ago

      I like to be optimistic and believe every article erodes their confidence in “alternative medicine”.

  • IninewCrow@lemmy.ca
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    8 months ago

    What about their effectiveness?

    I get that the first few versions might have stemmed the tide of the pandemic early on … but how effective are the new doses now?

    I’m not an antivacer but I do question the way the pandemic was handled and continues to be handled. I trust scientists, I trust the medical community, I trust our current level of knowledge and expertise … I even trust our government to do the best they can with what they have … I just don’t trust seeing big corporate interests quietly influencing everything in the background.

    I certainly don’t trust anyone or anything that reprimands me or is threatened by my questions or concerns.

    I would feel a whole lot better about all this if corporate and financial interests were completely disconnected from all our health care and pharmaceutical systems. Basically, anything that has to do with human bodily health should not be controlled or deeply influenced by monied interests.

    • NaibofTabr@infosec.pub
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      8 months ago

      Their efficacy has been heavily studied and proven.

      versions might have stemmed the tide of the pandemic

      This is straight-up weasel language. There is no (rational) question as to whether the vaccines reduced hospitalizations due to COVID-19, or contraction of COVID-19 in general.

      corporate and financial interests were completely disconnected from all our health care and pharmaceutical systems

      This is not realistic in the slightest. Reasearch requires resources and the time and effort of highly qualified people.

      • Cyborganism@lemmy.ca
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        8 months ago

        You don’t need to be so agressive.

        OP didn’t say that the vaccine didn’t work at first. It’s just that now development has a hard time to keep up with new mutations.

        Also, we don’t need multi billion dollar medical corporations to study and create vaccines. This could be done entirely through a government agency or ministry.

        I agree with OP about how much we should trust corporations. Their bottom line is to make a profit and they’ll do whatever they can to get there. They cut corners and hide facts to avoid losses.

        One such fact that was denied and for which you could get ridiculed was that a certain percentage of the population that received the COVID vaccine had symptoms afterwards that never went away. Like constant headaches and swelling of the brain. Now they explain these to you before you take new doses so that you know the risks. They’re small, but they can happen.

        In fact, ever since my last dose in August I’ve had constant headaches myself and I always feel hungover. It’s permanent. There’s nothing anyone can do about it. At this point I wonder if I should have taken it at all considering the I’ve had so the previous shots before. I only took it because I was traveling for a couple weeks and wanted to increase my chances of not getting sick.

      • IninewCrow@lemmy.ca
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        8 months ago

        I can agree and accept most debates about this and I probably agree with most of what you present. And I am vaxxed with six COVID vaccines at this point and chances are I’ll continue taking them with a lot of skepticism.

        The biggest issue I have is corporate control.

        I agree that research and development requires money … but that can be achieved through public funds and government programs. What do think is cheaper? Privately owned research that has to be paid for at a premium … or publically developed research that is made open and accessible for other researchers across the globe (who can then collaborate with each other instead of compete behind closed source patents and information)

        I trust the scientists and researchers that develop these medical break throughs … I just don’t trust the private CEOs that hire them or the corporations they work for.

      • SmoothIsFast@citizensgaming.com
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        corporate and financial interests were completely disconnected from all our health care and pharmaceutical systems

        This is not realistic in the slightest. Reasearch requires resources and the time and effort of highly qualified people.

        It’s extremely realistic, humanity makes the most progress when research does not need to create a monetary benefit. It allows us to explore ideas unabated. While these systems need funding we could take a 1% from military spending and invest with government resources. Hence why the mrna vaccines actually progressed so quickly, they were already being researched by the army for quick and rapid treatment of diseases during combat, i.e. just to solve the problem not just to profit from the tech, they lent that research out and gave grants to the corporations who developed and manufactured the covid vaccines. Internet, developed for combat communications not for profit. Most computer innovations came out of the space race, research without a profit motive. The ideas funded by corporate interests revolve around optimizing profit, not progress, which is why we get planned obsolescence, lack of rights to repair, massive healthcare costs needing insurance offsets, etc. I guarantee you can’t name an actual positive innovation that was spurred purely for profit and not bastardized in the name of profit from a century old idea people forgot about so the company could attribute genius to its wealthy founders crud copy and paste job.

      • kobra@lemm.ee
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        What if that 5% resist came with a temporary 36 hour debuff that made your character unplayable?

        Edit: Lmao at people downvoting what they think is an opinion? I’m just adding context that a lot of people do go through pretty severe symptoms. But sure, keep ignoring/downplaying them and complaining about low vaccination rates 😆

        • JonEFive@midwest.social
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          Show me data indicating that a significant number of people who receive the vaccine are affected to that extent.

          Anecdotally, nobody I know - including myself after being vaccinated multiple times - has had any significant negative reaction unless you count your arm being sore. “Unplayable” is extreme.

          Edit:Wild - thanks everyone for your input. This just says something about basing a knowledge on a limited sample size. I see that it really depends on the person now.

          I personally received the Pfizer shot as did just about everyone I know.

          • tony@lemmy.hoyle.me.uk
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            8 months ago

            My first and third vaccine knocked me out for 2 days at a time… unable to even get out of bed.

            Second one, after I’d booked time off work deliberately so I wouldn’t surprise anyone by not being there, I had no issues at all…

          • Catoblepas@lemmy.blahaj.zone
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            8 months ago

            The COVID boosters make me feel moderately sick and my arm very sore for 2-3 days, in a way most other vaccines don’t. The one time I had COVID I felt like I was one bad day away from winding up in the hospital for weeks, so I’ll take the vaccine every single time I can. If anything I think I feel so bad after the vaccine because COVID itself fucks me up so bad.

          • rigatti@lemmy.world
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            8 months ago

            My first shot, Moderna, knocked me out for about 36 hours. I could only muster up enough energy to get out of bed for a few minutes to eat a bit of cereal and drink some Gatorade. So there’s an anecdote from someone you don’t know.

            That being said, I’d still take that for the 5% resistance boost.

          • toasteecup@lemmy.world
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            My pre-wife was down for the count for 48-36 hours after getting a vaccine shot. The second round was a little better but not by much.

            I understand I’m just some random person on the Internet but I’m giving factual information in interest of continuing the discussion.

            The interesting thing is that while I was fine after the shots, I was not fine being sick with covid (post shot). I was on bed rest for about 5 days and all I could do was wake up, take aspirin and Tylenol, take a shower because covered in cold sweats, drink lemon ginger tea with honey to soothe the throat, watch 30ish minutes of YouTube and knock myself out with melatonin to repeat the cycle.

            She, on the other hand, was fine getting covid post shot.

            • JonEFive@midwest.social
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              Yeah, I got COVID after being vaxed too. My biggest symptom was just complete exhaustion and body aches. Mild cough for a couple days. It lasted about 5 days for me too. That said, I wonder how much worse it would have been if I wasn’t vaccinated.

              • toasteecup@lemmy.world
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                I can’t say I wondered how much worse it would have been without a shot but that’s because it was super bad for me with one ha.

          • time_lord@lemmy.world
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            8 months ago

            My work gave everyone who got it two days off to recover. It’s more like a 20% chance of a 24-48 hour debuff, but you can’t seriously tell me that you haven’t heard of anyone having side effects.

          • UID_Zero@infosec.pub
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            8 months ago

            I’ve had 5 shots of Moderna now, most recently last week. The first one made me feel miserable for a day. I was having chills, and my entire body was sore. I took several naps that day. The others made me sore and a little tired for a day.

            All told, not the worst side effects, but certainly more than a sore arm. And still entirely worth the mild inconvenience.

            I would call my first reaction nearly “unplayable.” I was having issues working (remotely even, a desk job), and I just wanted to sleep most of the day. But people react differently. Sounds like you had no issues, so good for you.

          • Metz@lemmy.world
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            8 months ago

            my second and third knocked me out for 3 full days. I was no longer able to get out of bed. I had severe chills and extreme nausea. I practically puked my guts out for 3 days. i know multiple other people that had very similar reactions.

          • ∟⊔⊤∦∣≶@lemmy.nz
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            8 months ago

            Reading all these people’s reactions makes me think I got the placebo. It did nothing to me. It was the pfizer edition, if that makes any difference.

          • uberkalden@lemmy.world
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            8 months ago

            Every shot after the first has knocked me on my ass for 24 hours minimum. Pro vax here. This is a real thing

        • tabular@lemmy.world
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          8 months ago

          On hardcore mode with permanent death the chance of a short term de-buff for a long term buff is worth it.

          Pick the right time so you don’t miss out on any one-time events if you’re unlucky.

    • DoomBot5@lemmy.world
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      8 months ago

      It’s as effective as the flu vaccine. Get the version that addresses the latest varients, as previous ones may not be as effective against it.

      • JonEFive@midwest.social
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        8 months ago

        Exactly. Some people get a flu shot every year. Now it’s going to be a flu shot and a covid shot.

        Virus evolves, scientists do their best to predict which particular variants are or will become most prevalent. Vaccinations are made and administered based on that data. Rinse and repeat.

        There are times when the models are wrong or variants progress in unexpected ways. In those cases you might see a mid-year booster.

        Vaccines don’t guarantee you won’t get sick, but they reduce the severity and time to recover if you do get sick with one of the relevant variants. They may even prevent the occurrence of most symptoms depending on the person. .